Disrupted cholinergic modulation can underlie abnormal gamma rhythms in schizophrenia and and auditory hallucination
نویسنده
چکیده
منابع مشابه
Disrupted cholinergic modulation can underlie abnormal gamma rhythms in the schizophrenia and and auditory hallucination
Auditory hallucination, one of the common symptoms of schizophrenia, has been thought to be induced by the failure of corollary discharge. It is consistent with the ‘dysconnectivity hypothesis’ that disrupted interareal interactions among brain regions underlie schizophrenia symptoms. However, the exact mechanisms underlying corollary discharge and its relation to the pathophysiology of schizop...
متن کاملDisrupted cholinergic modulation can underlie abnormal gamma rhythms in the schizophrenia
Gamma band oscillatory neural activity, considered critical in synchronizing brain areas, appears abnormal in patients with schizophrenia. Stimulus evoked gamma band power is lower, compared with healthy subjects, but baseline gamma power is higher. Based on the observation that cholinergic modulation regulates interactions between primary auditory cortex (A1) and an association cortex in the g...
متن کاملAttribution Bias in schizophrenian patients who have auditory hallucination
Introduction: Concerning cognitivism, psychotic experiences (hallucination) of schizophrenic patiets have been hypothesized to originate from a fundamentally cognitive biases. Methods: To explor the idea that attribution bias may underlin appearance of auditory hallucination, in the current descriptive study, a source-monitoring task were used to compare healthy controles with relatives of indi...
متن کاملLong-range synchrony of gamma oscillations and auditory hallucination symptoms in schizophrenia
Phase locking in the gamma-band range has been shown to be diminished in patients with schizophrenia. Moreover, there have been reports of positive correlations between phase locking in the gamma-band range and positive symptoms, especially hallucinations. The aim of the present study was to use a new methodological approach in order to investigate gamma-band phase synchronization between the l...
متن کاملCholinergic Neuromodulation Controls Directed Temporal Communication in Neocortex in Vitro
Acetylcholine is the primary neuromodulator involved in cortical arousal in mammals. Cholinergic modulation is involved in conscious awareness, memory formation and attention - processes that involve intercommunication between different cortical regions. Such communication is achieved in part through temporal structuring of neuronal activity by population rhythms, particularly in the beta and g...
متن کامل